Diabetic Ketoacidosis

What is diabetic ketoacidosis?

Diabetic ketoacidosis is a serious, life-threatening complication of high blood sugar. It may happen if you have type 1 diabetes, but rarely happens if you have type 2 diabetes. It is an emergency that must be treated right away. If ketoacidosis is not treated right away, it can cause diabetic coma or death.

How does it occur?

If you have diabetes and do not have proper treatment for it, you may develop this very dangerous complication called ketoacidosis. At first your blood sugar level may rise above normal. High blood sugar is called hyperglycemia. Hyperglycemia happens when you do not have enough insulin to get sugar out of your blood and into your cells. When the cells of the body can't use sugar for energy, they break down fat for energy. The fat byproducts (ketones) and high sugar level can cause ketoacidosis, a life-threatening chemical imbalance.

Reasons why your blood sugar may increase, even if you are taking insulin, include:

not getting enough insulin
not getting enough exercise
eating the wrong amounts or types of food, especially carbohydrates
not testing your blood sugar levels properly or regularly
having an insulin pump that stops working right
changing medicines.

However, ketoacidosis may occur even with proper treatment when there is a change in your life such as:

illness
infection
trauma
heart attack
surgery
pregnancy
other types of physical or emotional stress.

Sometimes the diagnosis of diabetes is made when ketoacidosis occurs. If you have type 1 diabetes, the pancreas stops making insulin. As a result, blood sugar may become very high, very fast. Sometimes it happens so fast that ketoacidosis symptoms are the first symptoms of type 1 diabetes.

What are the symptoms?

Symptoms of high blood sugar (hyperglycemia) include:

increased thirst
increased hunger
dry mouth
increased urination
blurred vision.

If you have ketoacidosis, you may also have these symptoms:

excessive urination (several quarts a day)
excessive thirstiness (several quarts a day)
fruity-smelling breath
rapid breathing
nausea or vomiting
confusion
tiredness.

The ketoacidosis symptoms leading to a diabetic coma usually happen gradually. In most cases it takes hours to a couple of days for ketoacidosis to cause a diabetic coma.

How is it diagnosed?

To diagnose ketoacidosis, your health care provider will ask about your medical history, review your symptoms, and examine you. Your provider will pay special attention to:

possible infection
the amount of fluids in your body
how clearly you are thinking
breathing difficulty
your heart and kidney function.

Your provider will do some tests to check the levels of sugar and other chemicals in your blood. If needed, your provider will also order other lab tests, a chest x-ray, or ECG.

How is it treated?

You may need to be treated at a hospital.
You will be given insulin as soon as ketoacidosis is diagnosed.
Your blood will be checked often for sugar levels and chemical balances.
You will be given intravenous (IV) fluids.
Your treatment will include antibiotic medicine if you have an infection.

How long will the effects last?

Ketoacidosis will continue until enough insulin is available to the body to achieve a normal blood sugar level and the insulin and fluids have restored chemical balance. If this condition is not treated, it can be fatal. With treatment, you will usually recover in hours to days.

What can be done to help prevent diabetic ketoacidosis?

To help take care of yourself and prevent ketoacidosis, follow these guidelines:

Keep your blood sugar level under control.
Eat a healthy diet.
Follow the physical activity or exercise plan your health care provider has recommended.
Check your blood sugar level as often as you and your provider have discussed.
Test for ketones in your urine if your blood sugar level is high or if you are ill or under more stress than usual.
Never take more insulin until you have double-checked your blood sugar reading and made sure your sugar level is too high. The symptoms of low blood sugar can be similar to those of high blood sugar.
Know the early signs and symptoms of ketoacidosis.
See your provider right away if you have symptoms of an infection, such as flu or a bladder infection.
Check your blood sugar more often if you think you are getting sick.
Keep extra insulin with you.
Carry an ID (such as a card or bracelet) that says you have diabetes, in case of an emergency.

Call your health care provider if your fasting blood sugar is 240 mg/dl or more for 2 days, especially if you also have vomiting or other symptoms of ketoacidosis.

Disclaimer: This content is reviewed periodically and is subject to change as new health information becomes available. The information provided is intended to be informative and educational and is not a replacement for professional medical evaluation, advice, diagnosis or treatment by a healthcare professional.

HIA File DHD3908F.HTM Release 9.0/2006