HEPATITIS VACCINE



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Hepatitis is an inflammation of the liver, caused by a virus. There are at least 5 types of viral hepatitis. Hepatitis A and hepatitis B are the most common. Fortunately, there are vaccines to prevent these two types of hepatitis.


Hepatitis A virus (HAV) is found in the stool (bowel movements) of people with Hepatitis A. Hepatitis A is usually spread by close contact or sometimes by eating food or drinking water contaminated with HAV. Hepatitis A vaccine provides long-term protection. The vaccine can be given to children 2 years or older and adults who are at risk for getting hepatitis A. The immunization is given in 2 doses 6 months apart.


The following people should get the immunization for hepatitis A:

  • people traveling or working in developing countries
  • people living in communities that have outbreaks of hepatitis A
  • men who have sex with men
  • people who use street drugs
  • people with chronic liver disease and
  • people who receive clotting factor concentrates

The most common side effects from the hepatitis A shots are soreness in the arm where the shot is given, and some adults have headaches. Very few adults may feel tired, and a few children may not be hungry after the shots. The side effects usually begin 3 to 5 days after the shot and may last 1 to 2 days.


Hepatitis B (HBV) is a much more serious disease. It can cause long-term illness that leads to liver damage, or liver cancer. Hepatitis B can be spread through contact with blood and other body fluids of an infected person. Many people who are infected with hepatitis B do not know how they got it. The ways that a person may get infected are:

  • unprotected sex with an infected person
  • sharing needles when using illegal drugs
  • being stuck by a used needle and
  • during birth when the virus passes from an infected mother to her baby

The hepatitis B vaccine is given in a series of 3 shots. The first dose can be given at any time. The second dose should be given 1 to 2 months after the first. And the third dose can be given 4 to 6 months after the first dose. Everyone younger than 18 years of age should get the hepatitis B vaccine. Babies of infected mothers can get the vaccine within 12 hours of being born. Other babies should receive the vaccine at 2 months of age.


Adults over 18 years of age who are at risk should get the vaccine. People who are at risk include:

  • people who have more than one sex partner in 6 months
  • men who have sex with other men
  • sex contacts of infected people
  • people who inject illegal drugs
  • healthcare and public safety workers who could come in contact with blood or other body fluids
  • household members of people with chronic hepatitis B infection and
  • people on hemodialysis

The side effects of hepatitis B vaccine are few. Some people will have some soreness where the shot was given for a day or two. Occasionally they may have a mild fever.


There is a new combination vaccine approved for protecting individuals 18 years or older against diseases caused by HAV and HBV. The vaccine combines the two already approved vaccines and is given in a three dose series at 0, 1, and 6 months. It has been proven as safe and effective as the two separate vaccines.


If there are questions about hepatitis A or B, or the vaccine for these, a healthcare provider should be contacted. People who are not sure if they should get the vaccine should also contact a provider.


Disclaimer: This content is reviewed periodically and is subject to change as new health information becomes available. The information provided is intended to be informative and educational and is not a replacement for professional medical evaluation, advice, diagnosis or treatment by a healthcare professional.


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McKesson Health Solutions LLC. All rights reserved.

Copyright © 2003 McKesson Health Solutions LLC All rights reserved.