ENDOCRINE DISORDERS



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The endocrine system is made up of glands that act as a control system for many body processes. It produces hormones that help coordinate the functioning of body organs and tissues. A hormone is a chemical substance made by an endocrine gland and carried by the bloodstream to another tissue where it exerts some effect. The amount of hormones released depends on the body's need at a given time. Hormone levels change in response to stress, infection, and other factors. Hormones affect growth and metabolism.


Endocrine disorders may occur when: there is too much, too little, or no hormone present; the hormone made is abnormal; or the target tissue cannot use the hormone. Common examples of endocrine disorders include:

  • overweight and obesity
  • osteoporosis
  • infertility
  • abnormal growth
  • diabetes
  • hypertension
  • high cholesterol and triglyceride levels
  • thyroid dysfunction and
  • pituitary hormone dysfunction

Exposure to infectious diseases, tissue death, tumors, heredity, use of steroid medications, nutritional deficiencies, and autoimmune problems (when the body attacks its own tissues) are some of the many reasons that the endocrine system may fail.


Symptoms of an endocrine disorder will vary based upon the affected tissue. Any unintentional change from what is normal should be mentioned to a healthcare provider. Some examples include unexplained symptoms of:

  • weight loss or gain
  • increased fatigue
  • darkening or thickening of the skin
  • increase or decrease in hairiness
  • change in libido or sexual functioning
  • changes in mood or personality and
  • increased thirst, hunger, or urination

Treatment is available for most endocrine problems. This may be done with hormone replacement or by destruction or removal of abnormal glandular tissue to control excess production of the hormone.


Disclaimer: This content is reviewed periodically and is subject to change as new health information becomes available. The information provided is intended to be informative and educational and is not a replacement for professional medical evaluation, advice, diagnosis or treatment by a healthcare professional.


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McKesson Health Solutions LLC. All rights reserved.

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